What is Excede? Every thing on 1 page

Are you looking for a reliable, long-lasting medication to help safely and effectively treat your livestock? What is Excede? EXCEDE® (Ceftiofur Crystalline Free Acid) Sterile Suspension may be the answer. This versatile treatment option is an FDA-approved product that offers extended coverage against some of the most common infections in cattle and swine, providing peace of mind to animal owners. In this blog post, we’ll explain more about EXCEDE®. And how it can be used to address a variety of ailments in cattle and swine. Keep reading to learn all there is to know.

  • EXCEDE STERILE–                                Ceftiofur injection, suspension.
  • Molecular Formula                               C19H17N5O7S3.
  • Molecular Weight                                             523.6.
  • Available in                                               100ml/ 250ml vials.
  • Storage                                                           20° to 25°C (68° to 77°F).
  • Excede Class                                            Ceftiofur is a beta-lactam antibiotic from the cephalosporin class.


Description of Excede

Excede is a brand name for ceftiofur crystalline-free acid. An animal health medication used to treat various bacterial infections. It is classified as a cephalosporin antibiotic, which effectively works to fight off harmful bacteria like Salmonella and E. coli that can cause disease in both small and large animals. 

Additionally, this potent antibiotic is effective against other bacterial infections found in dairy cows, horses, and swine. Excede provides relief quickly, often showing results within 48 hours of administration. Veterinarians around the country are thrilled with the results of this powerful medicine. And its ability to quickly treat myriad complications stemming from bacterial infection.

what is excede
what is excede


The federal government limits the use of this drug to licensed veterinarians and forbids its non-label utilization in cattle for disease prevention. Any attempt at administering it with unapproved doses, frequencies, durations or routes of administration will not be tolerated. Especially when involving major food-producing species/production classes.


  • EXCEDE Sterile Suspension protects against bovine respiratory disease (BRD). Caused by three common bacteria: M. haemolytica, P. multocida and H. somni – particularly in beef and dairy cattle at higher risk of infection than others.
  • EXCEDE Sterile Suspension is here to help treat bovine foot rot that can be associated with Fusobacterium necrophorum and Porphyromonas levii. Its special formula is designed for beef cattle, non-lactating dairy cows, and even lactating dairy ones.
  • It can provide dairy cattle with an effective solution to prevent the onset of acute metritis in their post-birth period. The powerful ceftiofur antibiotic treats bacteria associated with this condition. By this family members to stay healthy and productive.
  • EXCEDE Sterile Suspension helps combat the respiratory illness that affects beef, non-lactating dairy and lactating cattle. It’s indicated for treating bovine respiratory disease (BRD) caused by Mannheimia haemolytica, Pasteurella multocida or Histophilus somni. Giving your herd a fighting chance against shipping fever and pneumonia.

How to Order Prescriptions from PBS Animal Health

Ordering prescriptions from PBS Animal Health is a convenient and simple process. The first step is to locate what type of prescription your animal needs by working with your veterinarian. Once you have determined what product is required. You can visit the PBS Animal Health website and select what type of medication or product best fits your need.

For example, Excede, a broad-spectrum antibiotic for horses, helps treat bacterial infections. Besides ordering online, you can call PBS Animal Health directly to place an order on the phone and ask any questions throughout the ordering process. Regardless of what option fits you best. Using PBS Animal Health ensures you get quality products with fast service tailored to meet your needs at a great value.

Treatment of BRD and bovine foot rot

Proper treatment of bovine respiratory disease (BRD) and bovine foot rot is essential to ensure the health and welfare of cattle. Fortunately, there are a variety of options available for treating both conditions. BRD can be cured with antibiotics such as tilmicosin or trimethoprim-sulfonamides in powder form, tablets, injectables, or intramammary infusion.

Foot rot can be eliminated with therapeutic hoof trimming, and antibiotics applied topically on the affected tissue. The key to successfully treating either condition is early diagnosis and prompt intervention before it becomes too severe.

Keeping the animals adequately sheltered from extreme weather conditions and maintaining good hygiene standards help to reduce their chances and severity of BRD or foot rot infections.

Administration for the Base of the Ear: Toward the Opposite Eye Technique

Administration for the base of the ear can be a tricky technique to master, but the reward effectively provides relief from different types of physical pain. Through this method, a massage therapist uses their hand or fingers and presses at different points around the base of the ear to unlock muscle tightness and reduce tension.

This technique is known as the Opposite Eye Technique, as it works across opposite sides of the face. It involves administering direct pressure points to equalize both sides, creating approximate balance and symmetry.

The Opposite Eye Technique has been used successfully to alleviate neck and shoulder problems associated with conditions like TMJ and sinus congestion. With practice and some experimentation, any massage therapist can become comfortable using these pressure points to provide their clients with effective relief.


Administering the middle third of the ear requires a skilled and knowledgeable medical professional. It is important for anything done in the area to be precise, as the delicate structures surrounding it can cause significant damage if wrongly treated.

Special care must be taken to ensure any procedure in this region has minimal risks of infection or other complications. Additionally, administering medications or inserting instruments into this area must be met with extreme caution and precision.

This skill is particularly important for many medical professionals, such as otorhinolaryngologists, general practitioners, ENT specialists, and otologists.

Single Dose Regimen

The single-dose regimen is quickly becoming one of the most popular prescribing methods for doctors and their patients. This approach entails taking medications once or at the most twice a day.  Providing convenience and greater compliance with prescribed treatments.

This type of regime eliminates the need to remember to take multiple doses throughout the day while still ensuring that patients receive adequate dosages.

Similarly, it can reduce medication expenses due to lower numbers of individual pills purchased simultaneously. By opting for a single-dose regimen, you can achieve better treatment outcomes and save time and money.

what is excede

The base of the ear injection

Excede is a long-acting, sterile suspension of cefpodoxime proxetil. An antibiotic from the cephalosporin class treats certain infections in animals and humans. It comes as a solution injected just under the skin at the base of the ear. This area is a subcutaneous site. Because it has few pain-sensing nerve endings allowing for relatively little discomfort during injection. In addition, this area has few superficial blood vessels near the surface. It ensures that much of what is delivered into the body stays in place following injection resulting in more consistent. It prolonged coverage against infection for weeks and sometimes even months.


  • Take it seriously when using EXCEDE® (Ceftiofur Crystalline Free Acid).
  • ANTIBACTERIALS have the potential to create resistance. So a veterinarian must make decisions on usage.
  • It can target different bacteria and reduce inflammation. However, this ANTIBACTERIAL can also create immunotoxicity if not used correctly.
  • Always consult a trained veterinarian before administering EXCEDE® to ensure proper ANTIBACTERIAL usage.


EXCEDE® (Ceftiofur Crystalline Free Acid) is an antibiotic for treating respiratory tract infections in cattle and sheep. It rapidly eliminates the bacteria that cause these diseases, making it an effective treatment for affected animals.

As with any medication, there are concerns about potential adverse effects. However, extensive studies indicate that EXCEDE® has a favorable safety profile with minimal side effects. When used according to instructions. While some isolated instances of minor swelling or discomfort have been reported. This appears to be event-specific and occurs only rarely. Professional care and monitoring should always be adhered to prevent untoward reactions.

what is excede


EXCEDE (Ceftiofur Crystalline Free Acid) is a revolutionary solution for managing cattle health. Multiple doses can sustainably protect animals from harmful bacterial infections. As an injectable antibiotic while minimizing resistance development. But that’s not all — EXCEDE also has been proven to be extremely efficient in quickly reducing tissue and milk residue levels.

Its TMRD (Tissue and Milk Residue Depletion) system was developed to facilitate 180-day withdrawal times for dairy animals. Making treatment and routine tests quick and painless for cattle and farmers alike. With EXCEDE, the future of cattle health looks brighter than ever before.


  • Cattle suffering from BRD and bovine foot rot can be effectively treated with a single injection of ceftiofur equivalent in the base of their ear. To maximize effectiveness, one should administer 3mg CE per lb body weight (or 6.6 mg/ kg to metric-minded friends). Approximately 1.5 mL sterile suspension for every 100 lbs of cattle.
  • EXCEDE Sterile Suspension can be administered to beef and non-lactating dairy cattle in a single injection behind the ear, providing 6.6 mg of CE per kg of body weight (1.5 mL sterile suspension for every 100 lb).


Control of BRD

  • Give your bovine friends a shot of subcutaneous goodness in the middle or base of their ears. Administer 3.0 mg CE/lb (6.6mgCE/kg) body weight and watch them grow robustly with 1.5 mL sterile suspension per every 100 pounds they weigh.

Metritis Treatment

Inject dairy cows with a dose of 3.0 mg CE/lb (6.6mg CE/kg) into the skin at the back of their ear. It attaches to their head – that’s 1.5mL sterile suspension for every 100lbs. They’re carrying 72 hours after administering this first shot. You’ll need to do it again on its opposite side and watch your cattle thrive.

Safety Studies in Lactating Dairy Cattle

EXCEDE (Ceftiofur Crystalline Free Acid) is a powerful antibiotic for dairy cattle that have proven to be effective and offers significant safety benefits. Safety studies in lactating dairy cattle have demonstrated that when administered intravenously. EXCEDE offers no adverse effects on milk production or quality.

In fact, unlike many other antibiotics currently available. EXCEDE can provide successful treatment while having no impact on the performance or the composition of the cows’ milk. Further clinical trials suggest that this antibiotic reduces oxidative stress in freshly calved cows.

Thus they can develop their body systems with improved metabolic efficiency and greater protection against various diseases. All this suggests that EXCEDE is an ideal choice for dairy producers looking for reliable and safe treatments for their livestock.


EXCEDE (Ceftiofur Crystalline Free Acid) is an important antibiotic that packs a powerful punch when treating certain types of bovine respiratory disease. It is an injectable antibiotic and keep it in special storage conditions for the product to remain effective.

Keep EXCEDE stored between 36 degrees Fahrenheit and 46 degrees Fahrenheit. Make sure to keep this product away from light, heat, and extreme temperatures. Storing EXCEDE under these conditions will ensure that your cattle remain healthy and happy.


Where do you inject EXCEDE?

Answer: It is a long-acting, extended-release antibiotic for cattle that can provide up to 14 days of antimicrobial treatment in one injection. The intramuscular injection will administrate into the middle third of the neck muscle mass. At a single dosage ranging from 2.2 to 4.4 mg/lb body weight. Administering EXCEDE into other sites or muscles may increase tissue irritation, fever, and abscess formation at the injection site. 

Do you Need a Prescription for EXCEDE?

Answer: EXCEDE is a prescription product that requires a valid veterinary prescription. Your veterinarian can provide the necessary information and directions for proper use. Follow the directions on the prescription label. Store EXCEDE according to the storage conditions mentioned above.

What Class of Drug is EXCEDE?

Answer: Ceftiofur is a beta-lactam antibiotic from the Cephalosporin class.

Is EXCEDE Good for Pneumonia?

Answer:  Yes, EXCEDE (ceftiofur crystalline free acid) is an effective treatment for bovine respiratory disease caused by Mannheimia haemolytica, Pasteurella multocida and Histophilus somni. It is also effective in treating bacterial pneumonia caused by these bacteria. However, Keep in mind EXCEDE is a part of a treatment plan that includes supportive care and other measures as prescribed by your veterinarian. When combined with other recommended treatments. EXCEDE can help reduce the severity of the respiratory disease.

What is EXCEDE Used For in Cattle?

Answer:  EXCEDE (ceftiofur crystalline free acid) is an injectable antibiotic used in cattle. It treats and controls bovine respiratory disease caused by Mannheimia haemolytica, Pasteurella multocida and Histophilus somni. It is also effective in treating bacterial pneumonia caused by these bacteria. EXCEDE reduces the severity of metritis in freshly calved cows. It has improved fertility, milk production, and feed efficiency. In addition, EXCEDE has been shown to increase metabolic efficiency. It provide greater protection against bovine respiratory disease in feedlot cattle.

How often do you give EXCEDE to cattle?

Answer: When caring for cattle. It is important to remember that you should administer specific treatments and interventions regularly. Most commonly, this means giving EXCEDE once every seven days. However, depending on the age and breed of the animal as well as other factors such as activity level. This schedule can sometimes vary. Therefore, when administering EXCEDE to your cattle. It is important to consult with a veterinarian who can give you appropriate advice for dosing intervals depending on your specific circumstances.

Is EXCEDE an antibiotic?

EXCEDE is the first and only antibiotic that FDA has approved for horses. It offers a full 10-day course of therapy in just two treatments. By providing Ten days of therapy in just two treatments. Veterinarians can help optimize compliance and convenience by having to administer fewer doses.

How often do you give EXCEDE?

Answer: Shake well before using. Administer two intramuscular injections to horses, four days apart, at a dose of 3.0 mg/lb (6.6 mg/kg).


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